Mj. Crossley et Rc. Reid, CONCISE SYNTHESIS OF AROGENATE - A BIOSYNTHETIC PRECURSOR OF PHENYLALANINE AND TYROSINE, Journal of the Chemical Society, Chemical Communications, (19), 1994, pp. 2237-2238
A concise new route to arogenate 1-carboxy-4-hydroxy-2,5-cyclohexadien
-1-yl)alanine diammonium salt] 1 in which Michael addition of the anio
n derived from methyl 1,4-dihydrobenzoate 2 to the dehydroalanine deri
vative 3 is the key C-C bond-forming step is described.