FATAL INFECTIOUS-MONONUCLEOSIS IN AN 11-MONTHS-OLD GIRL

Fatal infectious mononucleosis is vary rare in the human population. O nly two case reports of girls suffering an Epstein-Barr virus-associat ed lymphoproliferation without evidence of an underlying immunodeficie ncy came to our knowledge. We report on the case of an 11-months-old g irl with fatal infectious mononucleosis. Some findings allow distinct delineation from previous reports. Firstly, the present ''pulmonary ly mphoid hyperplasia'' has been formerly described in patients with HIV infection exclusively. Secondly, only the EBV surface antigen LMP was expressed on infected B-cells. The nuclear antigen complex EBNA could not be demonstrated. Overall, the results suggest a so far unrecognise d type of EBV-associated lymphoproliferation in a female infant.