TRISOMY-5 AS THE SOLE CHROMOSOMAL ABNORMALITY IN A PRIMARY MUCOEPIDERMOID CARCINOMA OF THE MINOR SALIVARY-GLAND

Authors
ELNAGGAR AK LOVELL M KILLARY A BATSAKIS JG
Citation
Ak. Elnaggar et al., TRISOMY-5 AS THE SOLE CHROMOSOMAL ABNORMALITY IN A PRIMARY MUCOEPIDERMOID CARCINOMA OF THE MINOR SALIVARY-GLAND, Cancer genetics and cytogenetics, 76(2), 1994, pp. 96-99
Citations number
21
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
76
Issue
2
Year of publication
1994
Pages
96 - 99
Database
ISI
SICI code
0165-4608(1994)76:2<96:TATSCA>2.0.ZU;2-5
Abstract
We describe the cytogenetic findings in a moderately differentiated pr imary mucoepidermoid carcinoma of the base of the tongue. The only kar yotypic abnormality found in the primary culture of this neoplasm was trisomy 5. This finding is remarkably different from previous cytogene tic studies of mucoepidermoid carcinomas, which have shown heterogeneo us and unrelated chromosomal aberrations. Our results suggest that tri somy 5 may be an early aberration in the development of this neoplasm.