CYTOGENETIC OBSERVATIONS IN 13 CYSTADENOLYMPHOMAS (WARTHINS TUMORS)

The cytogenetic findings in 13 cultured Warthin's tumors (papillary cy stadenoma lymphomatosum) are reported. Only one case showed an abnorma l stemline. This was pseudodiploid and characterized by three differen t reciprocal translocations and one deletion. Small abnormal sidelines , however, were seen in three additional cases. All except one of the 12 tumors with a normal stemline contained variant cells. These showed a variety of numerical and/or structural aberrations. From this study it is obvious that to determine whether or not cytogenetically distin ctive subgroups actually exist in cystadenolymphomas (as in pleomorphi c adenomas) the number of cases must be greatly amplified.