BURKITT-LYMPHOMA WITH A DUPLICATION OF DER(8)T(2,8) - INTERPRETATION OF A COMPLEX KARYOTYPE BY CHROMOSOME PAINTING

Citation
Y. Vazquezmazariego et al., BURKITT-LYMPHOMA WITH A DUPLICATION OF DER(8)T(2,8) - INTERPRETATION OF A COMPLEX KARYOTYPE BY CHROMOSOME PAINTING, Cancer genetics and cytogenetics, 76(2), 1994, pp. 136-139
Citations number
11
Categorie Soggetti
Oncology,"Genetics & Heredity
ISSN journal
01654608
Volume
76
Issue
2
Year of publication
1994
Pages
136 - 139
Database
ISI
SICI code
0165-4608(1994)76:2<136:BWADOD>2.0.ZU;2-Z
Abstract
A 51-year-old male patient was diagnosed with Burkitt lymphoma 3 month s after cardiac transplantation. The bone marrow karyotype was very co mplex, and to better define the complex karyotype we used the in situ suppression hybridization technique. Previously we interpreted this ka ryotype to be: 48,XY;t(2;8) (p11;q24), +der(2)t(2;8)(p11;q24),del(2)(q 23), +7, +der(8)t(2;8)(p11;q24), +12, -13, -18, by G banding technique s, with a duplication of the t(2;8) derivatives. After in situ hybridi zation we changed to a: 48,XY,t(2;8)(p11;q24),t(2;18)(q23;q22), +7, der(8)t(2;8) (p11;q24), +12, -13, which implies duplication of only on e t(2;8) derivative.