AN EFFICIENT SYNTHESIS OF CHLORINATED IMIDAZOLES THROUGH TERT-BUTYLDIMETHYLSILYLOXY DERIVATIVES

Authors
ESTENNE G LECLERC G DODEY P RENAUT P
Citation
G. Estenne et al., AN EFFICIENT SYNTHESIS OF CHLORINATED IMIDAZOLES THROUGH TERT-BUTYLDIMETHYLSILYLOXY DERIVATIVES, Journal of heterocyclic chemistry, 31(5), 1994, pp. 1121-1123
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
31
Issue
5
Year of publication
1994
Pages
1121 - 1123
Database
ISI
SICI code
0022-152X(1994)31:5<1121:AESOCI>2.0.ZU;2-F
Abstract
The protection of 2-substituted imidazole-5-methanol derivatives by te rt-BDMS allowed the chlorination of the heterocycle in position 4 with good yield whereas direct chlorination on the imidazole alcohol was u nsuccessful.