THE MOLECULAR-STRUCTURE OF HUMAN ERYTHROPOIETIN

Citation
Rr. Romanowski et Aj. Sytkowski, THE MOLECULAR-STRUCTURE OF HUMAN ERYTHROPOIETIN, Hematology/oncology clinics of North America, 8(5), 1994, pp. 885
Citations number
34
Categorie Soggetti
Oncology,Hematology
ISSN journal
08898588
Volume
8
Issue
5
Year of publication
1994
Database
ISI
SICI code
0889-8588(1994)8:5<885:TMOHE>2.0.ZU;2-8
Abstract
The structure and function of human erythropoietin is under increasing ly intense study, owing both to the therapeutic importance of the horm one and to its biologic relevance. A combination of approaches using b iomechanical, immunochemical and molecular biologic techniques has pro vided new insights into erythropoietin's critical structural features. Both the protein's amino acid components and its attached complex car bohydrates contribute to its physiologic and pharmacologic properties.