CLINICAL-APPLICATION OF RECOMBINANT ERYTHROPOIETIN IN THE ANEMIA OF CHRONIC DISEASE

Authors
MEANS RT
Citation
Rt. Means, CLINICAL-APPLICATION OF RECOMBINANT ERYTHROPOIETIN IN THE ANEMIA OF CHRONIC DISEASE, Hematology/oncology clinics of North America, 8(5), 1994, pp. 933
Citations number
57
Categorie Soggetti
Oncology,Hematology
Journal title
Hematology/oncology clinics of North America → ACNP
ISSN journal
08898588
Volume
8
Issue
5
Year of publication
1994
Database
ISI
SICI code
0889-8588(1994)8:5<933:COREIT>2.0.ZU;2-6
Abstract
The anemia of chronic disease is associated with a blunted increase in erythropoietin (EPO) production in response to anemia, and with impai red erythroid progenitor response to EPO. Recombinant human (rh) EPO c an correct this impaired erythropoiesis in vivo and in vitro. Although most patients with the anemia of chronic disease are only moderately anemic, certain subsets may benefit from rhEPO therapy.