RAPID EVALUATION OF ETHANOL CONTENT AND METABOLISM IN HUMAN PLASMA USING QUANTITATIVE PROTON MAGNETIC-RESONANCE SPECTROSCOPY

Authors
DAVIN A VIONDURY J VIOUT P COZZONE PJ
Citation
A. Davin et al., RAPID EVALUATION OF ETHANOL CONTENT AND METABOLISM IN HUMAN PLASMA USING QUANTITATIVE PROTON MAGNETIC-RESONANCE SPECTROSCOPY, Alcohol and alcoholism, 29(5), 1994, pp. 479-483
Citations number
13
Categorie Soggetti
Substance Abuse
Journal title
Alcohol and alcoholism → ACNP
ISSN journal
07350414
Volume
29
Issue
5
Year of publication
1994
Pages
479 - 483
Database
ISI
SICI code
0735-0414(1994)29:5<479:REOECA>2.0.ZU;2-V
Abstract
Proton magnetic resonance spectroscopy (MRS) was used to assay ethanol in plasma. Ethanol concentrations determined by MRS and conventional enzymatic methods are in excellent agreement. fn addition to ethanol, acetone, acetate and beta-hydroxybutyrate can be quantified simultaneo usly in the same sample. Proton MRS of plasma offers a rapid evaluatio n of human ethanol metabolism and may be useful in screening for chron ic alcoholism.