This review examines the validity of the Michigan Alcoholism Screening
Test (MAST) as a screening instrument for alcohol problems. Studies t
hat compare the MAST-questionnaire with other defined diagnostic crite
ria of alcohol problems were retrieved through MEDLINE and a cross-bib
liographic check. A total of 20 validity studies were included. The st
udies varied considerably regarding the prevalence of alcohol problems
, the diagnostic criteria, and the examined patient categories. The MA
ST compared with other diagnostic criteria of alcohol problems gave va
lidity measures with the following span: predictive positive value (PV
pos) 0.24-0.96, predictive negative value (PVneg) 0.78- similar to 1,
sensitivity 0.36- similar to 1, and specificity 0.36-0.96. It appears
that the PVneg are high. Except from one study, the sensitivities (0.5
7- similar to 1) are also high. The PVpos and the specificities show s
ubstantial variations. The variables that seem to have the largest inf
luence on the PVpos seem to be the prevalence of alcohol problems, the
diagnostic method against which the MAST-questionnaire is validated,
and the populations on which the MAST is applied. The MAST should in t
he future be validated against internationally accepted diagnostic met
hods on populations with representative prevalences of alcohol problem
s.