BIOMETRY IN X-LINKED MEGALOCORNEA - PATHOGNOMONIC FINDINGS

Biometric study in a series of 11 affected males provides characterist ic findings. The patients present with a large cornea with short radiu s, very deep anterior chamber depth (AC depth) exceeding the normal me an value of plus 2 SD, and a short vitreous length. Calculation of the postlimbal depth; a method applied in this study to obtain informatio n about positioning of the iris and the lens, reveals a posterior posi tioning of the iris and lens. The posterior positioning of the iris an d lens was proved to occur at the expense of the vitreous. The importa nce of biometric data for diagnosis and for differential diagnosis in primary infantile glaucoma and other diseases with megalo-cornea is di scussed.