M. Kuipers et T. Schreuders, THE PREDICTIVE VALUE OF SENSATION TESTING IN THE DEVELOPMENT OF NEUROPATHIC ULCERATION ON THE HANDS OF LEPROSY PATIENTS, Leprosy review, 65(3), 1994, pp. 253-261
The early detection of the loss of protective sensation in leprosy pat
ients is vital if neuropathic ulceration and subsequent disabilities a
re to be avoided. The aim of this study was to find protective value o
f sensory thresholds in the hands of leprosy patients. Thresholds for
touch-pressure, vibration and temperature were assessed in areas on le
prosy-affected hands near ulcers or ulcer scars (LU-group), in areas w
ithout lesions (LN-group), and in controls (N-group). Semmes-Weinstein
monofilaments were used for testing the touch-pressure threshold (PST
), a biothesiometer for the vibration threshold (VST) and a Thermo Sen
sation Tester for the temperature threshold (TST). The distribution of
ulcers was about equal on palmar and dorsal aspects of the hands. In
the LU-group there was a negative response to SWF of 2.0 g in all pati
ents, while 74% could feel the 2.0 g in LN-areas and in N-areas 100% c
ould detect the 2.0 g SWF. In the LU-group about 11% felt 8 V VST, in
the LN-group about 60% and in the N-group 89%. Testing temperature sen
sation was given up prematurely because the results in controls were u
nsatisfactory. Both palmar and dorsal sides of the hands should be tes
ted for sensation. The thresholds for protective sensation are 2.0 g S
WF and 8 V for vibration sense. It is recommended that Semmes-Weinstei
n monofilaments should always be used for early detection of loss of p
rotective sensation.