TRANSPLANTATION OF FETAL AND XENOGENEIC NERVOUS-TISSUE IN PARKINSONS-DISEASE

A mixture of fetal human brain tissue and of neural primordia of Notch Drosophila melanogaster is transplanted to the ventrolateral thalamic nucleus of patients with Parkinson's disease in stage 3-4. Two kinds of operation are performed. In the first case cryodestruction of the z one of tissue implantation is performed before transplant, and in the second case this procedure is not performed. A stable effect manifeste d in the disappearance of tremor and rigidity is achieved for both kin ds of operation. When a transplant is performed without cryodestructio n, the effect does not manifest itself until 2 months postoperation. T he patients are followed up for 7-12 months postoperation. No side eff ects or relapses of Parkinson's disease are observed in this period.