AN EXPERIMENT WITH THE TRANSPLANTATION OF HUMAN FETAL TISSUES IN CHILDREN WITH DOWNS-SYNDROME

Citation
El. Panchenko et al., AN EXPERIMENT WITH THE TRANSPLANTATION OF HUMAN FETAL TISSUES IN CHILDREN WITH DOWNS-SYNDROME, Bulletin of experimental biology and medicine, 117(4), 1994, pp. 374-375
Citations number
3
Categorie Soggetti
Medicine, Research & Experimental
ISSN journal
00074888
Volume
117
Issue
4
Year of publication
1994
Pages
374 - 375
Database
ISI
SICI code
0007-4888(1994)117:4<374:AEWTTO>2.0.ZU;2-C
Abstract
Institutionalized infants With Down's syndrome were treated by transpl antation of human fetal tissue. In the control group without transplan tation 3 out of 7 children died of various infections during the first 6 months. Immunological tests found a more pronounced tendency toward a rise of IgG and a drop of IgA and IgM in the control group, while t here was only a slight tendency toward a drop of IgG and a rise of IgA and IgM in the group treated by transplantation of human fetal tissue . A more positive dynamics in the development of psychic functions was noted in children treated by transplantation as compared with the con trol group when the neurologic status was assessed, and 2 out of 6 chi ldren showed a tendency toward a decrease of the muscle hypotonia. Thi s is a preliminary report.