Vi. Kulakov et al., THE STATE OF AUTONOMIC REGULATION IN PATIENTS WITH POSTCASTRATION SYNDROME AFTER TRANSPLANTATION OF HUMAN FETAL TISSUES, Bulletin of experimental biology and medicine, 117(4), 1994, pp. 379-382
The functional state of the autonomic nervous system was evaluated in
38 women after total ovariectomy. Clinical analysis of autonomic disor
ders and challenging tests indicated the disturbance of autonomic regu
lation and inhibition of vascular reactivity against the background of
total autonomic lability. One month after transplantation of fetal hu
man tissues vascular responses were improved: the number of positive d
ilatatory reactions increased and moderate pulse waves were recorded.
The general condition of the patients improved, their work capacity in
creased, and sleep patterns normalized, which led to a reduction of an
xiety. However, the transplantations had varying effects on hot flashe
s, which may be associated with their diverse nature. The positive eff
ect that transplantation of fetal human tissues elicited in most patie
nts may be attributed to normalization of their hormonal status.