VESTIBULOPROTECTIVE ACTIVITY OF SEAL SERUM-PROTEINS

Authors
YASNETSOV VV GROMOV AN KISELEVA NM RUSAKOV DY BATRAKOV SG EVSTRATOV AV SHASHKOV VS
Citation
Vv. Yasnetsov et al., VESTIBULOPROTECTIVE ACTIVITY OF SEAL SERUM-PROTEINS, Bulletin of experimental biology and medicine, 117(4), 1994, pp. 443-444
Citations number
8
Categorie Soggetti
Medicine, Research & Experimental
Journal title
Bulletin of experimental biology and medicine → ACNP
ISSN journal
00074888
Volume
117
Issue
4
Year of publication
1994
Pages
443 - 444
Database
ISI
SICI code
0007-4888(1994)117:4<443:VAOSS>2.0.ZU;2-W
Abstract
Cat and rat experiments show that the protein fraction isolated from b lood serum of the Greenland seal has a protective activity against mot ion sickness. This activity is comparable to that of the classical ves tibuloprotector scopolamine and is greater than that of diprazine. Rad ioligand assay of the receptor binding showed that the serum protein f raction has the highest affinity for alpha(2)-adrenoreceptors, mu-opio id, and benzodiazepine receptors.