ENDOTOXIN AND SEPSIS RESEARCH - SIMPLISTIC APPROACHES HAVE FAILED

Authors
MACARTHUR RD BONE RC
Citation
Rd. Macarthur et Rc. Bone, ENDOTOXIN AND SEPSIS RESEARCH - SIMPLISTIC APPROACHES HAVE FAILED, Complications in surgery, 13(5), 1994, pp. 653-654
Citations number
NO
Categorie Soggetti
Medicine, General & Internal",Surgery
Journal title
Complications in surgery → ACNP
ISSN journal
1053749X
Volume
13
Issue
5
Year of publication
1994
Pages
653 - 654
Database
ISI
SICI code
1053-749X(1994)13:5<653:EASR-S>2.0.ZU;2-F
Abstract
The sepsis syndrome has been revealed to be incredibly complex, involv ing many mediators that we just now are starting to appreciate. Future clinical trials of new sepsis-related therapeutic products may need t o consider other endpoints in addition to mortality. Also, better iden tification of the subset of patients likely to benefit from these prod ucts is necessary, as are rapid diagnostic assays for endotoxin, tumor necrosis factor, and various cytokines.