A. Slungatallberg et al., NUCLEATED ERYTHROCYTES IN ENRICHED AND UNENRICHED PERIPHERAL VENOUS-BLOOD SAMPLES FROM PREGNANT AND NONPREGNANT WOMEN, Fetal diagnosis and therapy, 9(5), 1994, pp. 291-295
The presence of nucleated erythrocytes was studied before and after en
richment with immunomagnetic beads and monoclonal antiglycophorin A (a
nti-GPA) antibody in the peripheral venous blood of 11 pregnant women
at 10-16 weeks of gestation. Nucleated erythrocytes were identified by
alkaline phosphatase antialkaline phosphatase immunostaining by means
of anti-GPA antibody. In the unenriched cell samples, nucleated eryth
rocytes were found at frequencies of 1/2,800-1/83,000 in 6 cases. The
frequency of nucleated erythrocytes was increased up to 6 times by the
enrichment.