R. Schulz et al., SPONTANEOUS ECHO-CONTRAST IN THE LEFT-VEN TRICLE AS AN INDICATOR OF AN INCREASED RISK OF THROMBOEMBOLISM, Deutsche Medizinische Wochenschrift, 119(39), 1994, pp. 1317-1320
A 69-year old man with coronary heart disease complained of pain in hi
s right flank. He had dyspnoea, cough and fever up to 38,8 degrees C.
In addition to various positive indicators of inflammatory disease he
had a creatinine concentration of 1.8 mg/dl and an increased activity
of lactate dehydrogenase (1655 U/I). The chest radiograph demonstrated
pneumonia and computed tomography showed an infarct in the right kidn
ey. The ECG indicated atrial fibrillation with an irregular ventricula
r rate and left bundle branch block. Echocardiography demonstrated dil
atation of the left ventricle and. a thrombus adherent to the wall. Tr
ansoesophageal echocardiography additionally recorded spontaneous type
I echo-contrast, which disappeared after therapeutic heparinization.
Cerebral infarctions were shown by computed tomography, undertaken bec
ause of neurological symptoms. There were also signs of silent myocard
ial ischaemia. As a coronary artery bypass operation was contraindicat
ed, percutaneous transluminal balloon angioplasty was attempted but di
ssection occurred, causing irreversible cardiogenic shock of which the
patient died.