A total of 58 patients (116 eyes) with angioid streaks, referred to th
is department over 2 years (1990-1992), underwent a thorough ophthalmi
c examination, retinal fluorescein angiography, dermatological visit w
ith skin biopsy, and a series of other examinations (blood and biochem
istry, skull X-ray, vascular echo Doppler, abdominal ultrasound) and e
ye ultrasonography. Fifty patients (100 eyes, 86.2%) had pseudoxanthom
a elasticum (PXE). In the whole caselist, 21.6% had drusen compared wi
th 21.0% in the group with PXE. Both these findings are higher than th
ose published elsewhere. Drusen of the optic nerve head were also foun
d in 25% of the 16 eyes (8 patients) with angioid streaks but no PXE.
We believe we found a higher prevalence of drusen of the optic nerve h
ead in these patients with angioid streaks because we systematically e
mployed ultrasound.