INTELLIGENT OPTIMIZATION OF COLUMN TEMPER ATURES IN GAS-CHROMATOGRAPHY .1. THEORY

This paper gives the theory on intelligent optimization of column temp eratures in a given gas chromatographic column system. Based on the st ructure-retention relationship between solutes and solvents, and the d ependence of retention values on temperatures, most difficult separati ng component pairs and temperature separability range can be predicted , ideal optimum temperature programming, in which every step is determ ined by a most difficult separating component pair, can be further obt ained.