INHIBITORY EFFECT OF CALF FETUIN ON THE CYTOTOXIC ACTIVITY OF LAK CELL-DERIVED FACTORS AND TUMOR-NECROSIS-FACTOR

Authors
CHERTOV OY ERMOLAEVA MV SATPAEV DK SASCHENKO LP KABANOVA OD LUKANIDIN EM LUKJIANOVA TI REDCHENKO IV BLISHCHENKO LY GNUCHEV NV
Citation
Oy. Chertov et al., INHIBITORY EFFECT OF CALF FETUIN ON THE CYTOTOXIC ACTIVITY OF LAK CELL-DERIVED FACTORS AND TUMOR-NECROSIS-FACTOR, Immunology letters, 42(1-2), 1994, pp. 97-100
Citations number
15
Categorie Soggetti
Immunology
Journal title
Immunology letters → ACNP
ISSN journal
01652478
Volume
42
Issue
1-2
Year of publication
1994
Pages
97 - 100
Database
ISI
SICI code
0165-2478(1994)42:1-2<97:IEOCFO>2.0.ZU;2-P
Abstract
A protein-inhibiting LAK cell-mediated cytotoxicity was isolated from a LAK cell-conditioned medium. The N-terminal amino acid sequence of t his protein appeared to be identical to fetal calf fetuin. Pure isolat ed fetuin, as well as commercially available preparations of this prot ein, were shown to inhibit cytotoxic activity of both cytotoxic protei ns released by LAK cells and TNF.