Ke. Mckenna et D. Burrows, LEUKOPENIA, THROMBOCYTOPENIA AND LYMPHADENOPATHY ASSOCIATED WITH SULFASALAZINE, Clinical and experimental dermatology, 19(5), 1994, pp. 419-420
We report a 19-year-old woman with psoriasis who developed a severe al
lergic reaction within 1 week of commencement of sulphasalazine; her s
kin becoming erythrodermic with associated lymphadenopathy, leucopenia
and thrombacytopenia. Clinical signs and haematological abnormalities
rapidly returned to normal on discontinuation of sulphasalazine. It i
s important to monitor carefully haematological indices in the early s
tages of treatment with this drug.