Objective: To correlate the initial echographic findings in eyes with
infectious endophthalmitis with the visual prognosis and causative mic
roorganism. Design: A retrospective review of the clinical and standar
dized ocular echographic findings in eyes with infectious endophthalmi
tis was performed. Setting: University-based ophthalmology department.
Study Participants: One hundred thirty-seven eyes (136 patients) with
infectious endophthalmitis that were evaluated by the ocular echograp
hy service of the Doheny Eye Institute, Los Angeles, Calif, between Ja
nuary 1, 1981, and December 31, 1992. Results: Four findings on initia
l echography were associated with poor initial vision: dense vitreous
opacities, retinal detachment, macular detachment, and choroidal detac
hment. Five findings on initial echography correlated with poor final
vision: dense vitreous opacities, vitreous membranes, the presence of
retinal detachment, the extent of retinal detachment, and the presence
of choroidal detachment. Change (decrease) in vision during the follo
w-up period was associated with the presence of combined vitreous and
subhyaloid opacities, retinal detachment, and choroidal detachment. Al
l eyes with initially clear vitreous on ocular echography had either e
arly streptococcal or culture-negative endophthalmitis. Advanced strep
tococcal endophthalmitis correlated with the most severe vitreous infl
ammation, vitreous membranes, and the most extensive posterior vitreou
s detachment, whereas gram-negative endophthalmitis correlated with ch
oroidal detachment on initial echography. Stepwise logistic regression
analysis revealed that the presence of choroidal detachment, not gram
negative microorganisms, was the principal predictor of poor visual ou
tcome in these eyes. Conclusion: Ocular echography is a useful method
in the clinical evaluation and treatment of infectious endophthalmitis
, especially in eyes with opaque media.