SYNTHESIS AND STUDY OF (2S,4S)-4-ARYLAMINO-2-CARBOXY-5-PYRROLIDONES

Authors
KRASNOV VP NIZOVA IA SINITSYNA TA AVDYUKOVA NV
Citation
Vp. Krasnov et al., SYNTHESIS AND STUDY OF (2S,4S)-4-ARYLAMINO-2-CARBOXY-5-PYRROLIDONES, Russian chemical bulletin, 42(12), 1993, pp. 2001-2004
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
42
Issue
12
Year of publication
1993
Pages
2001 - 2004
Database
ISI
SICI code
1066-5285(1993)42:12<2001:SASO(>2.0.ZU;2-0
Abstract
(2S,4S)-4-Arylamino-2-carboxy-5-pyrrolidones were prepared by hydrolys is of dimethyl (2S,4S)-4-arylamino-N-phthaloylglutamtaes. The protonat ion constants of the arylamino group in the synthesized compounds were determined. The pyrrolidone ring is stable in acidic or neutral solut ions. The relative stability of the pyrrolidone ring in alkaline solut ions was studied by IR spectroscopy.