A new method for analyzing diagnostic accuracy is introduced. A diagno
stic accuracy curve may be obtained by plotting receiver operating cha
racteristic analysis data, P(A), as a function of exposure. By means o
f diagnostic accuracy curves the effects on diagnostic accuracy of tub
e potential, exposure, and size of carious lesions was studied. It was
found that the effect of the tube potential on the accuracy of caries
diagnosis is negligible. About 25% of the variation in diagnostic acc
uracy depends on the exposure and about 80% on lesion depth. With the
lesion depth constant, about 75% of the variance in diagnostic accurac
y depended on observer performance. The peak of a diagnostic accuracy
curve indicates optimum performance. This is found at an exposure that
gives a radiographic density of about 1 in enamel and dentin although
the tolerable exposure increases with increased lesion depth.