MULTICOMPONENT DETERMINATION OF CHLORINATED HYDROCARBONS USING A REACTION-BASED CHEMICAL SENSOR .1. MULTIVARIATE CALIBRATION OF FUJIWARA REACTION-PRODUCTS
Jm. Henshaw et al., MULTICOMPONENT DETERMINATION OF CHLORINATED HYDROCARBONS USING A REACTION-BASED CHEMICAL SENSOR .1. MULTIVARIATE CALIBRATION OF FUJIWARA REACTION-PRODUCTS, Analytical chemistry, 66(20), 1994, pp. 3328-3336
Multicomponent analysis for 1,1,1-trichloroethane, trichloroethylene,
and chloroform is demonstrated by partial least squares modeling of ab
sorbance data collected from the Fujiwara reaction of these analytes o
ver time. Optimal calibration times are determined for each analyte de
pendent upon its reaction rate. This is the simplest example of trying
to use the selectivity gained from a second data dimension or order.
Problems associated with first-order calibration are demonstrated when
interferences unaccounted for in the calibration model are present. D
etermination of 1,1,1-trichloroethane in the presence of the other two
species is also demonstrated using the generalized rank annihilation
method and trilinear decomposition for second-order calibration. A sub
sequent paper describes an approach using multivariate curve resolutio
n to extract the analytical information from the spectral and temporal
profiles of analytes in the Fujiwara reaction.