EFFECT OF FLAVONOIDS OVER LIPIDS IN RATS AND OVER DRUG-METABOLIZING-ENZYMES

The object of the investigation was the identification of the flavonoi ds of soya bean and testing them in rats against cholesterol and drug metabolizing enzymes. The cultivar UFV 5' was shown to contain formono metin, biochanin A, genistein, daidzein, naringenin, rutin, quercetin, morin, genistin, daidzin, quercitrin, khaempherol and isoquercitrin w hich were isolated, identified and tested. Animals that were administr ated formonometin, biochanin A, rutin, quercetin, quercitrin, isoquerc itrin showed lowest concentrations of lipids in the bloodstream and hi ghest concentrations of biliary salts, and no difference among them wa s observed for drug metabolizing enzymes.