Attitudes of people with HIV disease towards HIV have seldom been meas
ured. However, a well-established scale to measure attitudes toward ca
ncer in those with the disease, the 38-item Mental Adjustment to Cance
r (MAC) scale was modified to assess adjustment to HIV disease. We adm
inistered the scale to 107 Australian men with HIV infection, of whom
36 had an AIDS-defining condition, who were patients at an ambulatory
care facility and in a research study. The data were factor analyzed u
sing a method identical to that used in the development of the MAC sca
le to determine the latent dimensions of attitudes toward HIV/AIDS. Th
e Mental Adjustment to HIV scale (MAH) factor analysis revealed five f
actors: Helplessness-Hopelessness, Fighting Spirit, and Denial-Avoidan
ce as in the original MAC scale, plus a Fatalism subscale which also m
easured Preoccupation, and a new subscale, which measured Belief in In
fluencing the Course of the Disease. Together, these five factors acco
unted for half of the variance. These data suggest that while there ar
e similarities between mental attitude to cancer and mental attitude t
o HIV in the latent dimensions of the questionnaire items, there are a
lso some differences. Most significant is the belief in people with HI
V disease in being able to personally influence the course of the illn
ess, and the combination of Preoccupation with Fatalism. The five subs
cales of the MAH scale had Cronbach's alpha reliabilities between 0.80
and 0.55. The MAH appears to be a useful way to measure total attitud
es and subscale scores of people with HIV infection, including AIDS, t
o their disease.