ISOTOPE RENOGRAPHY IN CHILDHOOD ENURESIS

A retrospective review was performed of 100 enuretic children who unde rwent isotope renography during the period 1981-1989. Studies performe d were Tc99mDMSA studies for renal size and to detect renal scarring a nd renography using Tc99mDTPA or MAG3 to evaluate excretion and detect vesicoureteric reflux. Fifty-five children had microbiological eviden ce of urinary tract infection (UTI), and 16 (29%) of these had abnorma lities on their isotope studies. Forty-five had sterile urine and all had normal isotope studies. Thus despite recent reports of urodynamic abnormalities and increased incidence of reflux in patients with enure sis, our findings indicate that,:standard nuclear medicine renal studi es show few abnormalities in patients with monosymptomatic enuresis. T he 29% incidence of abnormal studies in patients with enuresis and UTI s suggests that the presence of infection should be an indication for further investigation in this subgroup of enuretic children.