HYDROGENATION OF DIMETHYL-1,3-DIOXOLAN-4-YL)-AZIRIDINE-2-CARBOXYLIC ACID ETHYL-ESTER

Authors
AMBROSI HD DUCZEK W RAMM M JAHNISCH K
Citation
Hd. Ambrosi et al., HYDROGENATION OF DIMETHYL-1,3-DIOXOLAN-4-YL)-AZIRIDINE-2-CARBOXYLIC ACID ETHYL-ESTER, Tetrahedron letters, 35(41), 1994, pp. 7613-7616
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
35
Issue
41
Year of publication
1994
Pages
7613 - 7616
Database
ISI
SICI code
0040-4039(1994)35:41<7613:HODA>2.0.ZU;2-G
Abstract
Hydrogenation of 1-benzyl-aziridine-2-carboxylic acid ethyl ester 1 yi elded the enantiomerically pure 1H-aziridine 2 or the beta-amino acid ester 3 as main products depending on the reaction time. The Z-protect ed derivatives of 2 and 3 were transformed into the gamma-lactones 4 a nd 5, respectively.