Protecting our groundwater from contamination is a major consideration
in the design of a herbicide discovery and evaluation programme. The
early stages of herbicide discovery and development should include cri
teria to select compounds with potentially low risks for groundwater c
ontamination. The scheme used by Sandoz Agro, Inc. to evaluate and sel
ect herbicides for commercialization is reviewed. Laboratory and green
house data, computer simulation to predict herbicide behaviour in the
soil environment, and field observations are included in the decision-
making process.