EFFECTS OF THE CENTRAL ANALGESICS MORADOL , TRAMAL, NUBAIN - NEUROPHYSIOLOGICAL ANALYSIS

The analysis of measurements of early and late components of somatosen sory (SSEP) and visual evoked potentials (VEP) in healthy examinees wa s used to compare the central mechanisms responsible for the analgesic action of moradol, tramal, and nubain. As compared to tramal and nuba in, moradol was found to cause a more profound increase in the amplitu de of early SSEP components. With this, all three agents were equal in suppressing the amplitude of late SSEP and VEP components. The effect s of the drugs on SSEP and VEP, as well as on the sensory and psychoem otional components of human pain perception were also evaluated. The p otential features of anesthesiological application of the drugs under study were discussed.