Mr. Handley et Me. Stuart, THE USE OF PROSTATE-SPECIFIC ANTIGEN FOR PROSTATE-CANCER SCREENING - A MANAGED CARE PERSPECTIVE, The Journal of urology, 152(5), 1994, pp. 1689-1692
A large nonprofit staff model Health Maintenance Organization experien
ced increased use of prostate specific antigen (PSA) as a screening te
st for prostate cancer beginning in May 1991. A critical evaluation of
the evidence in support of PSA screening was done and concluded that
the use of PSA to screen for prostate cancer did not meet the criteria
for an effective screening program. A guideline stating that PSA was
not recommended as a screening test was implemented focusing on a mode
l of shared decision making. PSA test ordering decreased significantly
when patients were fully informed about the evidence for PSA screenin
g. If PSA screening had continued at the peak rate, the cascade of int
ervention initiated by screening would have resulted in significant co
mplications and approximately $4,800,000 in increased costs.