CONTROL OF PROSTATE-CANCER WITH RADIOTHERAPY - LONG-TERM RESULTS

The long-term outcome for 1,245 patients with carcinoma of the prostat e treated with external beam radiation therapy is presented. The media n survival for all patients without evidence of distant metastases but irrespective of T stage of the primary tumor, histopathological grade or lymph node status was 10 years compared to 15 years for an age-mat ched cohort of California men. The cause specific survival at 15 years was 52%. The data base is subdivided into a series of subsets that de monstrate the impact of T stage, Gleason pattern score and lymph node involvement on long-term outcome. The best results were shown in stage s T1 and T2a cases with histopathologically proved negative lymph node s. Survival at 15 years was 53%, which was essentially identical to th e 55% survival rate of an age-matched cohort. The actuarial survival a t 15 years for all stages T1 and T2N0M0 cancer patients was 45% compar ed to 56% for an age-matched cohort.