Vesiculobullous lesions of esophagus in patients post bone marrow tran
splantation may occur due to infectious agents or acute graft-versus-h
ost disease (GVHD), We report the case of a patient who developed a la
rge bulla in the esophagus as a result of chronic GVHD. Potential etio
logies, diagnosis and management of bullous esophagitis are reviewed.