Nv. Gribkova et al., EFFICACY OF AN ANTIVIRAL FACTOR OBTAINED FROM INFECTED CHICK-EMBRYO FIBROBLASTS IN EXPERIMENTAL HERPES INFECTION, Voprosy virusologii, 39(4), 1994, pp. 182-184
Treatment of mice with an antiviral factor obtained from the culture m
edium of infected chick embryo fibroblasts protected them against leth
al meningoencephalitis caused by herpes simplex virus. The degree of p
rotection varied from 50 to 75% depending on the virus dose, the route
of infection, and the mode of the antiviral factor application.