USE OF MONOCLONAL-ANTIBODIES FOR INFLUENZ A-VIRUS DETECTION

The possibilities of using influenza A (Leningrad) 385/80 (H3N2) virus matrix protein-specific FITC-labeled D8 monoclonal antibodies in immu nofluorescence assays were investigated. The virus antigen accumulatio n was detected in chorioallantoic cells of chick embryos. Exhibiting t he type-specific properties, the fluorescent antibodies stain the peri nuclear space, cytoplasmic membrane, and granular structures in the cy toplasm of infected cells. The haemagglutination test titres in the co rresponding specimens were at least 1:16.