SKIN CARCINOMA, HPV-5 - REVEALING ROLE OF A PUVATHERAPY WITH HIGH TOTAL-ENERGY

Introduction. HPV 5 is an opportunistic oncogenic virus found mainly i n patients with verruciform epidermodysplasia or in certain immunodepr essed patients. Case. We report the case of a 48-year-old patient who developed, over a 5 year period, 30 skin carcinomas after prolonged pu vatreatment. HPV 5 was identified. The course has been stable under tr eatment with etretinate and alpha-interferon. Comments. The role of ul traviolet irradiation as a carcinogenic agent is raised by this observ ation, both as a primary factor and as a local factor favouring immuno suppression and proliferation of opportunistic HVP.