GENETIC-CONTROL OF YEAST-CELL MORPHOLOGY

Citation
Vn. Egorova et Kl. Lakhchev, GENETIC-CONTROL OF YEAST-CELL MORPHOLOGY, Genetika, 30(8), 1994, pp. 1036-1042
Citations number
37
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00166758
Volume
30
Issue
8
Year of publication
1994
Pages
1036 - 1042
Database
ISI
SICI code
0016-6758(1994)30:8<1036:GOYM>2.0.ZU;2-I
Abstract
Yeast cell phenotype and morphology result from the interaction of two processes, polarized growth, on the one hand, and cytokinesis with su bsequent division of the cell wall, on the other. Imbalance of the equ ilibrium of these two principal processes may lead to the occurrence o f yeast morphological mutants that generate rough colonies. Two types of such mutants exist, Rgh and Rpm. The Rgh mutants have ellipsoid cel ls and either form chains or generate clumps at high frequency. These changes in heterothallic strains of saccharomyces occur due to recessi ve mutations in any of 11 nonlinked genes. In homothallic strains of s accharomyces, the trait Rgh depends on the complementary interaction o f one dominant and two recessive genes. Rpm mutants generate rough col onies, which contain elongated cells that give rise to pseudomycelium. The mutants obtained are recessive and occur in six nonlinked genes. The Rpm mutants represent an example of the manifestation of mycelium - yeast dimorphism in fungi, and this case may be regarded as a simple morphogenetic model.