Jz. Ayanian et al., KNOWLEDGE AND PRACTICES OF GENERALIST AND SPECIALIST PHYSICIANS REGARDING DRUG-THERAPY FOR ACUTE MYOCARDIAL-INFARCTION, The New England journal of medicine, 331(17), 1994, pp. 1136-1142
Background. The respective roles of generalist and specialist physicia
ns in the care of patients are currently a matter of debate. Informati
on is limited about the knowledge and practices of generalist and spec
ialist physicians regarding conditions that both groups treat, such as
myocardial infarction. Methods. We therefore surveyed 1211 cardiologi
sts, internists, and family practitioners in the states of New York an
d Texas about four treatments demonstrated by randomized clinical tria
ls to be associated with improved survival after myocardial infarction
(thrombolytic therapy, immediate and long-term use of aspirin, and lo
ng-term use of beta-blockers) and two treatments for which such eviden
ce is lacking (diltiazem for patients with pulmonary congestion and pr
ophylactic lidocaine). We asked physicians about the effect of each tr
eatment on survival and the likelihood that they would prescribe each
class of drugs. Results. For the four beneficial treatments, the cardi
ologists believed more strongly than the internists and family physici
ans that survival was improved by the treatment, and they were more li
kely to prescribe these drugs (P<0.001). For example, 94.1 percent of
cardiologists said they were very likely to prescribe thrombolytic age
nts to treat an acute myocardial infarction, as compared with 82.0 per
cent of internists and 77.3 percent of family practitioners. Conversel
y, for the two treatments for which trials showed no evidence of a sur
vival benefit, cardiologists were less likely than internists and fami
ly practitioners to think there was such a benefit and less likely to
prescribe the drugs (P<0.001). For example, 4.7 percent of cardiologis
ts reported that they were very likely to use prophylactic lidocaine,
as compared with 13.1 percent of internists, and 16.5 percent of famil
y practitioners. When we used logistic regression to adjust for potent
ial confounders, all the differences between the cardiologists and the
internists and family practitioners remained significant (P<0.02). Co
nclusions. Internists and family practitioners are less aware of or le
ss certain about key advances in the treatment of myocardial infarctio
n than are cardiologists. This finding underscores the need to improve
the dissemination of information from clinical trials to generalist p
hysicians, particularly if they are to have an enlarged role in the ev
olving health care system.