The biochemical route is identified to be one of the simplest and chea
pest means by which valuable chemicals are being synthesized. Microorg
anisms play a vital role in carrying out these processes. However, the
kinetic studies relevant to this process is scarce. Most often inhibi
tion effects due to either cells or substrates or products affect the
performance of such processes. This paper deals with the study of vari
ous model equations for substrate inhibition kinetics. An attempt has
been made to study the applicability of various model equations for su
bstrate inhibited systems by fitting their experimental data and evalu
ating various parameters including the standard deviations in each cas
e. Finally, a new model has been brought out which gives the best fit
for almost all the systems.