EFFECTS OF VENLAFAXINE IN THE SLEEP ARCHITECTURE OF RATS

Authors
SALINPASCUAL RJ MOROLOPEZ ML
Citation
Rj. Salinpascual et Ml. Morolopez, EFFECTS OF VENLAFAXINE IN THE SLEEP ARCHITECTURE OF RATS, Psychopharmacology, 129(3), 1997, pp. 295-296
Citations number
10
Categorie Soggetti
Neurosciences,Psychiatry,"Pharmacology & Pharmacy
Journal title
Psychopharmacology → ACNP
Volume
129
Issue
3
Year of publication
1997
Pages
295 - 296
Database
ISI
SICI code
Abstract
Different venlafaxine doses (1, 5, and 10 mg/kg) and saline solution w ere administered to ten male Wistar rats (Latin-Square design). Compar ed with saline, venlafaxine produced a dose-related supression of REM sleep and an increase in wake time while slow wave sleep was reduced. This effect is similar to the one that has been reported with some tri cyclic antidepressants.