THE MANY GUISES OF AMYLOIDOSIS - CLINICAL PRESENTATIONS AND DISEASE ASSOCIATIONS

Amyloidosis occurs in association with many diseases and can also be i diopathic. It is usually a systemic disease with variable presentation s. The diagnosis should be suspected in patients with unexplained prot einuria, cardiomyopathy, congestive heart failure, peripheral neuropat hy, carpal tunnel syndrome, macroglossia, or hepatosplenomegaly. Amylo idosis generally has a poor prognosis and responds poorly to therapy. Much needs to be learned about its pathogenesis and treatment possibil ities.