Citation
G. Murin et K. Micieta, FATE OF METHYL METHANESULFONATE-INDUCED DNA DOUBLE-STRAND BREAKS DURING THE RECOVERY IN VICIA-FABA ROOTS, BIOLOGIA, 49(3), 1994, pp. 347-352
Citations number
NO
Categorie Soggetti
Biology
Journal title
BIOLOGIA
ISSN journal
00063088
→ ACNP
Volume
49
Issue
3
Year of publication
1994
Pages
347 - 352
Database
ISI
SICI code
0006-3088(1994)49:3<347:FOMMDD>2.0.ZU;2-H
Abstract
Methyl methanesulphonate (MMS-) induced DNA double-strand breaks (DSBs
) were detected in V. faba root tips by neutral DNA elution at MMS-con
centrations of 4 mM, 5 mM, 6 mM and 10 mM. Evaluation of the dose depe
ndent response to the mutagen revealed unexpected results. After a rec
overy time of 24 h of mutagen - treated roots the amount of DSBs incre
ased 1.8 up to 2.6 times.