Purpose: Current information concerning the results of surgical revisi
on of threatened infrainguinal vein grafts is largely limited to in si
tu conduits. Infrainguinal grafts may be threatened by intrinsic graft
lesions or significant stenosis in the adjacent inflow or outflow art
eries. To assess the results of operative revision of infrainguinal re
versed vein grafts, we reviewed our experience with surgical revision
of threatened infrainguinal reversed vein grafts identified through a
program of postoperative clinical and vascular laboratory graft survei
llance. Methods: All patients who underwent surgical revision of a thr
eatened but patent infrainguinal reversed vein graft from January 1987
through April 1993 were identified through review of our vascular reg
istry. Data mere analyzed for type of vein used, date of original reve
rsed vein graft, clinical and vascular laboratory findings leading to
reversed vein graft revision, results of preoperative angiography, pat
ient risk factors, operative techniques and complications, and long-te
rm assisted primary graft patency and limb salvage. Results: Ninety-si
x patients with 100 infrainguinal reversed vein grafts (69) femoral-po
pliteal, 31 femoral-tibial) underwent 117 surgical vein graft revision
s or inflow procedures during the study period Eighty-one percent of t
he original reversed vein grafts consisted of a single segment of grea
ter saphenous vein. All revised grafts had at least a 50% stenosis in
the graft itself or the proximal or distal artery. A single revision w
as performed in 85 grafts, two revisions in 13 grafts, and three revis
ions in two grafts. There were nine (8%) isolated inflow procedures, e
ight (7%) vein patch angioplasties, 62 (53%) interposition vein grafts
, and 29 (25%) vein graft extensions to a new distal anastomotic site.
The remaining nine (8%) procedures consisted of combinations of the a
bove. Median time to primary graft revision after initial graft implan
tation was 15 months (range 2 days to 316 months). Mean time to second
ary revision after primary revision was 21 months. Operative mortality
was 0.9%. Cumulative assisted primary patency of the original grafts
revised for stenotic lesions was 99%, 96%, and 92% at 1, 3, and 5 year
s, respectively. Limb salvage was 99%, 97%, and 97% at 1, 3, and 5 yea
rs, respectively. Conclusions: Although surgical revision of reversed
vein graft requires much use of alternative vein sources, these proced
ures can be performed with minimum mortality and provide excellent ass
isted primary graft patency and limb salvage.