THE SCHIZOSACCHAROMYCES-POMBE-RAD1 GENE CONSISTS OF 3 EXONS AND THE CDNA SEQUENCE IS PARTIALLY HOMOLOGOUS TO THE USTILAGO-MAYDIS-REC1 CDNA

We show that the rad1 gene of Schizosaccharomyces pombe is comprised o f three exons and encodes a protein of 37 kDa. A cDNA clone containing these three exons complements the sensitivity of the rad1-1 mutant to ultraviolet and gamma-radiation and to hydroxyurea. The newly identif ied ORF of the rad1 gene was found to exhibit partial homology to the REC1 gene of Ustilago maydis. These two genes share putative functiona l similarities in their respective organisms.