SISTER-CHROMATID EXCHANGES IN EPILEPTIC PATIENTS ON ANTICONVULSANT THERAPY

Authors
SARDAS S ADA M KARAKAYA AE AYDIN N
Citation
S. Sardas et al., SISTER-CHROMATID EXCHANGES IN EPILEPTIC PATIENTS ON ANTICONVULSANT THERAPY, Mutation research. Section on environmental mutagenesis and related subjects, 313(1), 1994, pp. 21-24
Citations number
16
Categorie Soggetti
Genetics & Heredity","Environmental Sciences
Journal title
Mutation research. Section on environmental mutagenesis and related subjects → ACNP
ISSN journal
01651161
Volume
313
Issue
1
Year of publication
1994
Pages
21 - 24
Database
ISI
SICI code
0165-1161(1994)313:1<21:SEIEPO>2.0.ZU;2-5
Abstract
Sister-chromatid exchanges (SCE) have been studied to analyze genotoxi c effects in epileptic patients on anticonvulsant therapy. All patient s had an increased frequency of SCE per metaphase (p < 0.001) compared to controls, indicating a genotoxic effect of anticonvulsant drugs.