RISK-FACTORS FOR ACUTE NON-A, NON-B-HEPATITIS AND THEIR RELATIONSHIP TO ANTIBODIES FOR HEPATITIS-C VIRUS - A CASE-CONTROL STUDY

Authors
MELE A SAGLIOCCA L MANZILLO G CONVERTI F AMOROSO P STAZI MA FERRIGNO L RAPICETTA M FRANCO E ADAMO B PALUMBO F SBREGLIA C PANA A PASQUINI P
Citation
A. Mele et al., RISK-FACTORS FOR ACUTE NON-A, NON-B-HEPATITIS AND THEIR RELATIONSHIP TO ANTIBODIES FOR HEPATITIS-C VIRUS - A CASE-CONTROL STUDY, American journal of public health, 84(10), 1994, pp. 1640-1643
Citations number
11
Categorie Soggetti
Public, Environmental & Occupation Heath","Public, Environmental & Occupation Heath
Journal title
American journal of public health → ACNP
ISSN journal
00900036
Volume
84
Issue
10
Year of publication
1994
Pages
1640 - 1643
Database
ISI
SICI code
0090-0036(1994)84:10<1640:RFANNA>2.0.ZU;2-W
Abstract
A case-control study was carried out comparing 333 case subjects with non-A, non-B hepatitis and 1095 hospital control subjects. Of 333 case subjects, 197 (59%) were positive for hepatitis C antibody (anti-HCV) . Excluding blood transfusion and intravenous drug use, surgical inter vention and dental therapy were strongly associated with anti-HCV-posi tive cases: in particular, obstetric and gynecology surgical intervent ion was found to be strongly associated with HCV positivity (odds rati o [OR] = 32: 95% confidence interval [CI] = 7, 147). Raw shellfish con sumption was a risk factor for anti-HCV-negative cases (OR = 2.2; 95% CI = 1.0, 5.1), thus suggesting an enterically transmitted virus in sp oradic non-A, non-B hepatitis in Italy.