The magnetic resonance (MR) images of 11 cases of gastrointestinal lym
phoma are presented. The findings include irregularly thickened mucosa
l folds, irregular submucosal infiltration, annular constricting lesio
n, exophytic tumor growth, mesenteric masses, and mesenteric/retroperi
toneal lymphadenopathy. The tumors were homogeneous and intermediate i
n signal intensity on T1-weighted images. Heterogeneously increased si
gnal intensities were noted on T2-weighted images. There was mild to m
oderate enhancement after intravenous administration of gadolinium dim
eglumine (Gd-DTPA). The submucosal tumor infiltration might be outline
d between the strongly GD-DTPA-enhanced mucosa and the low-intensity m
uscular layer. In one case that received tumor resection, the patholog
ical examination showed destruction of most parts of the muscular laye
r, and the MR images did not disclose the low-intensity muscular zone.